Wednesday, January 30, 2013

Infections in the Mouth Can Be Heart Disease


Many people with heart attacks do not have traditional risk factors, such as hypertension, diabetes, elevated levels of cholesterol, smoking, obesity, lack of physical activity, and heredity. Poor oral hygiene is suspected as a risk factor related to cardiovascular events such as heart attack and stroke.Bacteria in the oral cavity often leading to a heart valve infection is Streptococcus viridan

The mouth can be the dirtiest part of the body. Nearly 700 species of bacteria in the oral cavity. There are different types of heart disease risk factors alone.
Related to oral hygiene, the researchers found patients with coronary heart disease (CHD) with infection in the oral cavity have twice the risk of heart attack is higher.
CHD is a narrowing of the arteries / coronary arteries due to fatty deposits, cholesterol, and calcium in the arterial wall (atheroma plaques).
One sign of gum disease is bleeding gums, especially when brushing or flossing your teeth. When tissue injury to the gums, bacteria will easily enter the blood stream directly from the mouth. When bacteria get into the blood circulation in contact with plaque (cholesterol deposits in the artery walls), the formation of blood clots, and even the process of early atherosclerosis.
Mechanism
Various theories linking gum disease with CHD. It started from the inflammation of the gums. Inflammation stimulates the formation of atheroma plaques. Bacterial protein that can initiate the process of plaque formation are heat shock proteins (HSP). These proteins work as molecular chaperone, which serves to stabilize other proteins, folding and helped to pass through the cell membrane.
Because heat shock proteins are produced by humans and bacteria, the immune system is not able to distinguish between the body's own HSP and from bacteria.
This causes the immune system to attack its own proteins. Furthermore, white blood cells (macrophages) will "eat" protein. The series of inflammatory processes in the vessel wall can induce atherosclerosis.
Analysis of atheroma plaques in the walls of coronary artery angioplasty action taken when evidence of white blood cells called T cells
Thus, no matter what your physical prime, when the mouth is not clean, you may experience serious health problems such as heart attack or stroke.
Certain proteins in bacteria making platelets (platelet) easy to stick, as the beginning of the process of blood clot formation. When you have formed a blood clot is large enough, could potentially clog arteries. If the blockage occurs in the arteries of the heart will cause a heart attack, and when the brain arteries clog will be a stroke.
Not only CHD, oral infections can also cause heart valve infection. Patients with heart valve abnormalities, such as narrowing or leaking, prone to infections of the various components of the heart valves (endocarditis).
Bacteria in the oral cavity often leading to a heart valve infection is Streptococcus viridan. The entry of bacteria from the oral cavity into the bloodstream facilitates abnormal germ reaches the heart cavity. Germs can form a growing colony, called vegetation. The growth of germs causing worse damage the heart valves.
Vegetation bacteria also can stimulate the formation of blood clots that cause serious problems, such as blockage with bacterial infection to the brain resulting in a stroke and brain inflammation, damage to other organs such as the kidneys, lungs, and heart rhythm abnormalities.
Identification of bacteria
The researchers identified pathogens associated with gum infections, the bacteria Tannerella forsythensis and Prevotella intermedia, were associated with an increased risk of heart attack.
Various studies have concluded that the overall number of bacteria, regardless of the type of bacteria, the role is more important to heart health. This is one reason efforts to prevent gum infection and minimize the amount of bacteria in the oral cavity is important.
The results show the importance of Scottish Study toothbrushes every time after eating. Research involving 11,000 people showed up, people who just do brush your teeth once a day had a 70 percent increased risk of heart disease than people who do brush your teeth at least twice a day.
In observations occurred during the 8 years of cardiovascular events (stroke and heart attack) as 555 cases, 170 cases of which resulted in death and most in the group that only did toothbrush once a day.
The above is confirmed, in determining prevention strategies to reduce the incidence of cardiovascular disease, the involvement of dentists no small role.
Sources: http://health.kompas.com/read/2013/01/30/06251468/

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